Enhanced Degradation of Phospholipids by Phospholipase A2 in Liver of Carbon Tetrachloride-Treated Rat
نویسندگان
چکیده
*To whom correspondence should be addressed: the Department of Health Chemistry, Graduate School of Pharmaceutical Sciences. The University of Tokyo. Tel.: +81-3-5481-4720; Fax: +81-3-3818-3173; E-mail: [email protected] Present address: Fundamental Research Laboratory, KOSE Corporation, Department of Microbiology and Molecular Pathology, Faculty of Pharmaceutical Sciences, Teikyo University, Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University Enhanced Degradation of Phospholipids by Phospholipase A2 in Liver of Carbon Tetrachloride-Treated Rat
منابع مشابه
Enhanced Therapeutic Benefit of QuercetinPhospholipid Complex in Carbon Tetrachloride-Induced Acute Liver Injury in Rats: A Comparative Study
Quercetin is a typical flavonoid with diverse biological effects, attributable to its free radical scavenging activity. Bioavailability of quercetin aglycone and its glycosides is an important factor for its antioxidant activity in vivo. A severe limitation exists and is imputable to very poor absorption of quercetin when administered orally. To overcome this limitation, development of a value ...
متن کاملاثر عصارهی هیدروالکلی برگ گیاه غافث (Agrimonia eupatoria L.) بر سمیت کبدی در موشهای صحرایی نر القا شده با تتراکلرید کربن
Background and Objective: Carbon tetrachloride (CCl4) is a toxic agent leading to hepatotoxicity. The aim of this study was to investigate the effect of Agrimonia eupatoria leaf hydroalcoholic extract (AEE) on carbon tetrachloride induced rat liver. Materials and Methods: In this study, 42 male rats were randomly allocated to 6 groups: the control group receiving normal saline, 2ml/kg, ip and ...
متن کاملINFLUENCE OF GLYCOSAMINOGLYCANS ISOLATED FROM THE RAT LIVER WITH VARIOUS STAGES OF CARBON TETRACHLORIDE-INDUCED FIBROSIS UPON COLLAGEN FIBRILLOGENESIS IN VITRO
The influence of glycosaminoglycans (GAG) on collagen fibrillogenesis in vitro was investigated. GAG and collagen were isolated from the liver of rats treated with carbon tetrachloride at various time intervals (3-16 weeks). It was found that GAG obtained from the fibrotic liver accelerated collagen fibril formation. This effect was more evident in a solution of type I collagen than type II...
متن کاملHepatoprotective Effect of Ficus carica Leaf Extract on Mice Intoxicated with Carbon Tetrachloride
Protective action of Ficus carica leaf ethanolic extract (obtained by maceration) was evaluated in an animal model of hepatotoxicity induced by carbon tetrachloride (CCl4). Male albino mice were divided into six groups. group I was normal control group; group II received olive oil (CCl4 solvent), groups III-VI received CCl4. After inducing hepatic damage, group III served as control for CCl4; a...
متن کاملHepatoprotective Effect of Ficus carica Leaf Extract on Mice Intoxicated with Carbon Tetrachloride
Protective action of Ficus carica leaf ethanolic extract (obtained by maceration) was evaluated in an animal model of hepatotoxicity induced by carbon tetrachloride (CCl4). Male albino mice were divided into six groups. group I was normal control group; group II received olive oil (CCl4 solvent), groups III-VI received CCl4. After inducing hepatic damage, group III served as control for CCl4; a...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2001